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CHIAO, PAUL J

One or more keywords matched the following items that are connected to CHIAO, PAUL J

Item Type	Name
Academic Article	Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin.
Academic Article	Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway.
Academic Article	Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells.
Academic Article	Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter.
Academic Article	The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer.
Academic Article	EGFR-induced and PKCe monoubiquitylation-dependent NF-?B activation upregulates PKM2 expression and promotes tumorigenesis.
Academic Article	Disruption of the NF-?B/I?Ba Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons.
Concept	Humans
Concept	Chlamydia trachomatis
Concept	Smoking
Concept	Benzenesulfonates
Concept	Cyclic AMP Response Element-Binding Protein
Concept	Body Mass Index
Concept	Protein Binding
Concept	I-kappa B Kinase
Concept	Tumor Burden
Concept	Brain Neoplasms
Concept	DNA-Binding Proteins
Concept	Transforming Growth Factor beta
Concept	NF-kappa B
Concept	Aged, 80 and over
Concept	Receptors, Transforming Growth Factor beta
Concept	Lentivirus
Concept	Benzamidines
Concept	Biomarkers, Tumor
Concept	Chromosome Banding
Concept	Protein Biosynthesis
Concept	Mice, Knockout
Concept	Animals
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Blotting, Northern
Concept	Aged
Concept	Cricetinae
Concept	Insulin-Like Growth Factor Binding Protein 2
Concept	Mice, Inbred NOD
Concept	Mesocricetus
Concept	Retroviridae
Concept	9,10-Dimethyl-1,2-benzanthracene
Concept	Binding Sites
Concept	Papillomaviridae
Concept	Mice, Inbred BALB C
Concept	NF-kappa B p50 Subunit
Concept	Blotting, Western
Concept	bcl-2-Associated X Protein
Concept	Mice, Nude
Concept	Adenoviridae
Concept	Mice, SCID
Concept	NF-E2-Related Factor 2
Concept	Polypyrimidine Tract-Binding Protein
Concept	I-kappa B Proteins
Concept	bcl-X Protein
Concept	Benzamides
Concept	Breast Neoplasms
Concept	B-Lymphocytes
Concept	Fusion Proteins, bcr-abl
Concept	Biopsy, Needle
Concept	Genes, bcl-2
Concept	Mice
Concept	Immunoglobulin kappa-Chains
Concept	Models, Biological
Concept	rhoA GTP-Binding Protein
Concept	Middle Aged
Concept	Carcinoma, Ductal, Breast
Concept	Base Sequence
Concept	Mice, Mutant Strains
Concept	RNA-Binding Proteins
Concept	Mice, Inbred ICR
Concept	Adult
Concept	Mice, Inbred C57BL
Concept	Boronic Acids
Concept	Mice, Transgenic
Concept	Transforming Growth Factor beta1
Concept	Chickens
Concept	F-Box Proteins
Concept	Drosophila
Academic Article	A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth.
Academic Article	N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation.
Academic Article	NF-kappaB in pancreatic cancer.
Academic Article	Overexpression of synuclein-gamma in pancreatic adenocarcinoma.
Academic Article	Inhibition of constitutively activated nuclear factor-kappaB radiosensitizes human melanoma cells.
Academic Article	Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.
Academic Article	Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors.
Academic Article	Desensitization of NF?B for overcoming chemoresistance of pancreatic cancer cells to TNF-a or paclitaxel.
Academic Article	The proto-oncogene bcl-3 encodes an I kappa B protein.
Academic Article	Susceptibility to ras oncogene transformation is coregulated with signal transduction through growth factor receptors.
Academic Article	Modulation of differentiation in PA-1 human teratocarcinoma cells after N-ras oncogene-induced tumorigenicity.
Academic Article	PA-1, a human cell model for multistage carcinogenesis: oncogenes and other factors.
Academic Article	Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines.
Academic Article	Autoregulation of I kappa B alpha activity.
Academic Article	Inhibition of nuclear factor-kappaB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis.
Academic Article	Bcl-2 suppresses apoptosis resulting from disruption of the NF-kappa B survival pathway.
Academic Article	DNA adducts in human pancreatic tissues and their potential role in carcinogenesis.
Academic Article	Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells.
Academic Article	The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells.
Academic Article	Inhibition of the transcription factor nuclear factor-kappa B by adenoviral-mediated expression of I kappa B alpha M results in tumor cell death.
Academic Article	Prognostic factors in resectable pancreatic cancer: p53 and bcl-2.
Academic Article	Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis.
Academic Article	Function of nuclear factor kappaB in pancreatic cancer metastasis.
Academic Article	Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms.
Academic Article	NF-kappa B activation is not required for Chlamydia trachomatis inhibition of host epithelial cell apoptosis.
Academic Article	Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response.
Academic Article	Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter.
Academic Article	In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis.
Academic Article	Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer.
Academic Article	Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma.
Academic Article	NF-kappa B as a target for cancer therapy.
Academic Article	Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death.
Academic Article	Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.
Academic Article	Secreted interleukin-1alpha induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-kappaB.
Academic Article	Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity.
Academic Article	Study human pancreatic cancer in mice: how close are they?
Academic Article	Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKK? signaling cascade.
Academic Article	Activation of ribosomal protein S2 gene expression in a hamster model of chemically induced oral carcinogenesis.
Academic Article	Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
Academic Article	drp, a novel protein expressed at high cell density but not during growth arrest.
Academic Article	Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.
Academic Article	E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities.
Academic Article	The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration.
Academic Article	The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis.
Academic Article	Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation.
Academic Article	Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
Academic Article	Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells.
Academic Article	Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
Academic Article	Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells.
Academic Article	Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase.
Academic Article	Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells.
Academic Article	Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models.
Academic Article	LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis.
Academic Article	14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition.
Academic Article	Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype.
Academic Article	Modulation of pancreatic cancer chemoresistance by inhibition of TAK1.
Academic Article	Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-?B Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells.
Academic Article	Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA.
Academic Article	Restoring apoptosis in pancreatic cancer cells by targeting the nuclear factor-kappaB signaling pathway with the anti-epidermal growth factor antibody IMC-C225.
Academic Article	Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis.
Academic Article	Identification of an autoregulatory feedback pathway involving interleukin-1alpha in induction of constitutive NF-kappaB activation in pancreatic cancer cells.
Academic Article	NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity.
Academic Article	Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation.
Academic Article	TrkBT1 induces liver metastasis of pancreatic cancer cells by sequestering Rho GDP dissociation inhibitor and promoting RhoA activation.
Academic Article	KrasG12D-induced IKK2/?/NF-?B activation by IL-1a and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.
Academic Article	Kras, Pten, NF-?B, and inflammation: dangerous liaisons.
Academic Article	Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin.
Academic Article	In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer.
Academic Article	Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation.
Academic Article	SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium.
Academic Article	Mechanisms of Overcoming Intrinsic Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma through the Redox Modulation.
Academic Article	ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
Academic Article	Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer.
Academic Article	Melatonin overcomes gemcitabine resistance in pancreatic ductal adenocarcinoma by abrogating nuclear factor-?B activation.
Academic Article	IL1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NF-?B Activation.
Academic Article	Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.
Academic Article	FBW7 (F-box and WD Repeat Domain-Containing 7) negatively regulates glucose metabolism by targeting the c-Myc/TXNIP (Thioredoxin-binding protein) axis in pancreatic cancer
Academic Article	IGFBP2 activates the NF-ÎºB pathway to drive epithelial-mesenchymal transition and invasive character in pancreatic ductal adenocarcinoma
Academic Article	IL1 receptor antagonist inhibits pancreatic cancer growth by abrogating NF-ÎºB activation
Academic Article	Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer.
Academic Article	Transforming Growth Factor-? Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors.
Academic Article	FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer.
Academic Article	IGFBP2 Activates the NF-?B Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma.
Academic Article	Inhibition of Pancreatic Cancer by RhIL1RA-Response.
Academic Article	NEMO peptide inhibits the growth of pancreatic ductal adenocarcinoma by blocking NF-?B activation.
Academic Article	Amphiregulin in Cancer: New Insights for Translational Medicine.
Academic Article	SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer.
Academic Article	Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression.
Academic Article	TAK-ing aim at chemoresistance: The emerging role of MAP3K7 as a target for cancer therapy.
Academic Article	The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1.
Academic Article	Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
Academic Article	Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.
Academic Article	EGFR-Induced and PKCe Monoubiquitylation-Dependent NF-?B Activation Upregulates PKM2 Expression and Promotes Tumorigenesis.
Academic Article	Two Birds with One Stone: Therapeutic Targeting of IL1a Signaling Pathways in Pancreatic Ductal Adenocarcinoma and the Cancer-Associated Fibroblasts.
Concept	Bevacizumab
Concept	Bortezomib
Concept	Forkhead Box Protein O3
Concept	Zinc Finger E-box-Binding Homeobox 1
Concept	NF-KappaB Inhibitor alpha
Concept	F-Box-WD Repeat-Containing Protein 7
Concept	Zinc Finger E-box Binding Homeobox 2
Concept	Baculoviral IAP Repeat-Containing 3 Protein
Concept	B7-H1 Antigen
Academic Article	Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma.
Academic Article	Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling.
Academic Article	Circular RNAs regulate cancer-related signaling pathways and serve as potential diagnostic biomarkers for human cancers.
Academic Article	Cisplatin and gemcitabine exert opposite effects on immunotherapy with PD-1 antibody in K-ras-driven cancer.
Academic Article	3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma.
Academic Article	Recombinant Thrombomodulin Has Anti-tumor Effects and Enhances the Effects of Gemcitabine for Pancreatic Cancer Through G-protein Coupled Receptor 15.
Academic Article	Circulating levels of hydroxylated bradykinin function as an indicator of tissue HIF-1a expression.

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